Gastrointestinal/Nutrition: Week 4

Course Information Year 2 Courses: Gastro-Intestinal/Nutrition

Viral and Parasitic Infections of the Gut, IBS, Liver (Anatomy & Physiology of the Liver)

Mid-Term

Thanksgiving Break

See Blackboard (Content>Lecture Materials or Content> Lab Materials) for Weekly Objective and PowerPoint slides.

• Objectives - Week 4

Boards and Beyond - Suggested

List of Boards and Beyond Videos along with length

Note: If you are logged into Board and Beyond, these links should go directly to the video.

This Week:  169 minutes total

Gastroenterology

• Bile - Boards and Beyond

  • Video

  17 minutes
  Listed in Week 1 and Week 4

• Bilirubin - Boards and Beyond

  • Video

  29 minutes
  Listed in Week 1 and Week 4

• Liver Disease - Boards and Beyond

  • Video

  22 minutes
  Assigned in Weeks 4 & 6

• Cirrhosis - Boards and Beyond

  • Video

  23 minutes
  Assigned in Weeks 4 & 6

• Gallstones - Boards and Beyond

  • Video

  20 minutes

• Biliary Disorders - Boards and Beyond

  • Video

  14 minutes

• Inflammatory Bowel Disease - Boards and Beyond

  • Video

  20 minutes
  Assigned in Weeks 3 & 4

• Colon Cancer - Boards and Beyond

  • Video

  24 minutes
  Assigned in Weeks 3 & 4

Lecture 13 - Parasitic Pathogens of Diarrhea

Read Relevant Sections in the Chapters Below
(see Objectives)

• Ch 72 Intestinal and Urogenital Protozoa IN: Medical Microbiology

• Ch 74 Nematodes IN: Medical Microbiology

• Ch 75 Trematodes IN: Medical Microbiology

Lecture 14 - Viral Pathogens of Diarrhea

• Gastrointestinal Tract section of Ch 38 Role of Viruses in Disease IN: Medical Microbiology

  stop at Exanthem, Hemorrhagic Fevers, and Arthritides

• Adenoviruses IN: Murray Medical Microbiology

  .

• Ch. 51 Rotoviruses in Reoviruses IN: Murray Medical Microbiology

  see also scenario at top of the chapter

Lecture 15 - Alcohol & the Liver: Portal Hypertension AND Lecture 16 - Fatty Liver & Autoimmune Liver Disease

• Fatty Liver Disease section of Ch 18 Liver and Gallbladder IN: Robbins and Cotran Pathologic Basis of Disease

  Lecture 15 & 16

• Nonalcoholic Fatty Liver Disease (NAFLD) section of Ch 18 Liver and Gallbladder IN: Robbins and Cotran Pathologic Basis of Disease

  Lecture 15

• Autoimmune Hepatitis section of Ch 18 Liver and Gallbladder IN: Robbins and Cotran Pathologic Basis of Disease

  Lecture 16

• Ch 329 Approach to the Patient with Liver Disease

  Lecture 15 & 16

• Ch 334 Chronic Hepatitis IN: Harrison’s Principles of Internal Medicine

  Lecture 16

• Ch 335 Alcoholic Liver Disease IN: Harrison’s Principles of Internal Medicine

  Lecture 15 & 16

• Ch 336 Nonalcoholic Fatty Liver Diseases and Nonalcoholic Steatohepatitis IN: Harrison’s Principles of Internal Medicine

  Lecture 15

• Ch 337 Cirrhosis and Its Complications IN: Harrison’s Principles of Internal Medicine

  Lecture 15 & 16

• Ch 401 The Metabolic Syndrome IN: Harrison’s Principles of Internal Medicine

  Lecture 16

Lecture 17- IBS, Constipation and Related Disorders

• Ch 62 Drugs Used in the Treatment of Gastrointestinal Diseases IN: Basic & Clinical Pharmacology

  Also assigned for Lecture 7 and 11

• Ch 320 Irritable Bowel Syndrome IN: Harrison’s Principles of Internal Medicine

Lecture 18 - Porphyria

• Ch 407 Hemochromatosis IN: Harrison’s Principles of Internal Medicine

• Ch 408 Wilson’s DiseaseIN: Harrison’s Principles of Internal Medicine

• Ch 409 The Porphyrias IN: Harrison’s Principles of Internal Medicine

• Porphyria

  Bissell DM, Anderson KE, Bonkovsky HL. Porphyria. N Engl J Med. 2017 Aug 31;377(9):862-872. doi: 10.1056/NEJMra1608634.

• A13 Atlas of Liver Biopsies IN: Harrison’s Principles of Internal Medicine

Lab Readings

• Inflammatory Bowel Disease section of Ch 17 The Gastrointestinal Tract IN: Robbins and Cotran Pathologic Basis of Disease

  Stop after Other Causes of Chronic Colitis (before Graft-Versus-Host Disease)

• Polyps section of Ch 17 The Gastrointestinal Tract IN: Robbins and Cotran Pathologic Basis of Disease

  Stop after Tumors of the Anal Canal (before Hemorrhoids)

Enrichment Readings

Health Care Costs

• High and rising health care costs. Part 1: seeking an explanation

  more… less…

  Bodenheimer T. High and rising health care costs. Part 1: seeking an explanation. Ann Intern Med. 2005 May 17;142(10):847-54.

GI Infections

• Clostridioides difficile Infection

  Guh AY, Kutty PK. Clostridioides difficile Infection. Ann Intern Med. 2018 Oct 2;169(7):ITC49-ITC64. doi: 10.7326/AITC201810020.

• Ch. 23 Gastrointestinal Tract Infections IN: Mims’ Medical Microbiology

  more… less…

  Goering RV, Dockrell HM, Zuckerman M, Chiodinia PL. Gastrointestinal tract infections. In: Goering RV, Dockrell HM, Zuckerman M, Chiodinia PL, eds. Mims’ Medical Microbiology, 6th e. Philadelphia, PA: Elsevier; 2019.

Gut Microbiome

• Analysis of the Human Gut Microbiome and Association With Disease

  Wu GD, Lewis JD. Analysis of the human gut microbiome and association with disease. Clin Gastroenterol Hepatol. 2013 Jul;11(7):774-7. doi:
  10.1016/j.cgh.2013.03.038. Epub 2013 Apr 30.

• The gut microbiota and host health: a new clinical frontier

  Marchesi JR, Adams DH, Fava F, Hermes GD, Hirschfield GM, Hold G, Quraishi MN, Kinross J, Smidt H, Tuohy KM, Thomas LV, Zoetendal EG, Hart A. The gut microbiota and host health: a new clinical frontier. Gut. 2016 Feb;65(2):330-9. doi:10.1136/gutjnl-2015-309990. Epub 2015 Sep 2.

Liver Metabolism

• Metabolic Functions of the Liver

  more… less…

  Mitra V, Metcalf J. Metabolic functions of the liver. Anasethesia & Intensive Care Medicine. 2009; 10(7):334-5. doi: 10.1016/j.mpaic.2009.03.011

• Ch 28 transport & Metabolic Functions of the Liver - Functions of the Liver section IN: Ganong’s Review of Medical Physiology

  more… less…

  Chapter 28. Transport & Metabolic Functions of the Liver. In: Barrett KE, Boitano S, Barman SM, Brooks HL. eds. Ganong’s Review of Medical Physiology, 24e New York, NY: McGraw-Hill; 2012. http://accessmedicine.mhmedical.com/content.aspx?bookid=393§ionid=39736772.

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Captured on May 5, 2021