Course Information Year 2 Courses: Derm/Heme/Musculoskeletal
Week 5
pages 1295-1310 and 1313-1315
Steinberg MH. Sickle cell anemia, the first molecular disease: overview of molecular etiology, pathophysiology, and therapeutic approaches. ScientificWorldJournal. 2008 Dec 25;8:1295-324. doi: 10.1100/tsw.2008.157.
Robbins and Cotran Pathologic Basis of Disease
Chapter 5 - Genetic Disorders - sections (see below)
(stop at Defects in Receptors and Transport Systems)
9th ed: pages 141-143
Sections: Autosomal Recessive Disorders, X-Linked Disorders, and Biochemical and Molecular Basis of Single-Gene (Mendelian) Disorders)
8th ed: pages 141-143)
(stop at Thalassemia Syndromes section)
9th ed: pages 635-638
8th ed: pages 645-648
Hoffbrand’s Essential Haematology
Chapter 7 - Genetic Disorders of Haemoglobin - section on Sickle Cell Anaemia
(will need to scroll down to get to Sickle Cell section of the page or use navigation in the table of contents on the left)
8th ed: pages 89-94
7th ed: pages 215-233
6th ed: pages 99-104
Ch 23 Haemopoietic Stem Cell Transplantation IN: Hoffbrand’s Essential Haematology
8th ed: pages 281-295
7th ed: pages 250-263
6th ed: pages 297-313
Lymphoma & Related Disorders 1 & 2
Ch 19 Hodgkin Lymphoma IN: Hoffbrand’s Essential Haematology
8th ed: pages 229-237
7th ed: pages 205-212
6th ed: pages 245-252
Ch 20 Non-Hodgkin Lymphomas IN: Hoffbrand’s Essential Haematology
8th ed: pages 238-254
7th ed: pages 213-227
6th ed: pages 253-271
Ch 21 Multiple Myeloma and Related Plasma Cell Neoplasms IN: IN: Hoffbrand’s Essential Haematology
8th ed: pages 255-271
7th ed: pages 228-241
6th ed: pages - 272-287
Leukemia and Related Disorders 1 & 2
Ch 13 Acute Myeloid Leukaemia IN: Hoffbrand’s Essential Haematology
8th ed: pages 158-171
7th ed: pages 145-155
6th ed: pages 178-190
Ch 14 Chronic Myeloid Leukaemia IN: Hoffbrand’s Essential Haematology
8th ed: pages 172-181
7th ed: pages 156-164
6th ed: pages 191-199
Ch 15 Myeloproliferative Disease IN: Hoffbrand’s Essential Haematology
8th ed: pages 182-195
7th ed: pages 165-176
6th ed: pages 200-213 (chapter name: The non-leukaemic myeloproliferative neoplasms)
Ch 16 Myelodysplastic Syndromes IN: Hoffbrand’s Essential Haematology
8th ed: pages 196-205
7th ed: pages 177-185
6th ed: pages 214-222
Ch 17 Acute Lymphoblastic Leukaemia IN: Hoffbrand’s Essential Haematology
8th ed: pages 206-218
7th ed: pages 186-196
6th ed: pages 223-232
Ch 18 The Chronic Lymphoid Leukaemias IN: Hoffbrand’s Essential Haematology
8th ed: pages 219-228
7th ed: pages 197-204
6th ed: pages 234-244
Read PRIOR to TBL Session
See Blackboard for slides associated with this presentation
Chapter 11 - Bleeding and Thrombotic Disorders
read pages 281-286 (Introduction up to Bleeding Disorders) - AND-
pages 308-315 Thrombotic Disorders to the end of the chapter.
Objectives:
1. List the major clinical indications for both anticoagulant and anti-platelet therapies
2. Describe the mechanism of action of each anticoagulant and each anti-platelet agent in clinical use
3. Identify the tests used to monitor each anticoagulant
4. Provide the name of the reversal agent for each anticoagulant
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Source:
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Captured on May 5, 2021